The Quick Report

The 10 Largest Single-Cell Organisms in the World

When you think of single-celled organisms, you probably imagine something microscopic. But some of them are surprisingly huge! These giant cells can be seen with the naked eye and challenge what we think we know about biology.

From deep-sea mysteries to slime molds that solve mazes, here are the biggest single-cell organisms on Earth.

1. Caulerpa taxifolia

Caulerpa taxifolia Feather algae
Openverse

This invasive green algae looks like a regular plant, but it’s actually one giant cell! It spreads quickly, covering ocean floors and outcompeting other marine life.

2. Valonia ventricosa (Bubble Algae)

Alga burbuja (Valonia ventricosa), Zanzíbar, Tanzania, 2024-05-29, DD 62
Openverse

Also known as bubble algae, this bright green sphere can grow up to 4 inches wide. It’s one of the largest known single cells and can be found in tropical oceans.

3. Xenophyophores

Xenophyophore (10.1016-j.ejop.2020.125715) Figure 15
Openverse

These deep-sea giants are made of a soft, jelly-like material and can reach several inches in diameter. They thrive in extreme environments, including the deepest trenches of the ocean.

4. Gromia sphaerica

Gromia sphaerica
Youtube | Texas Science

This mysterious organism looks like a rolling mud ball. Found in the deep sea, it moves by leaving behind strange trails on the ocean floor.

5. Acetabularia (Mermaid’s Wineglass)

File:Elysia timida (Risso, 1818) sur Acetabularia acetabulum (Linnaeus).jpg
Openverse

This delicate, umbrella-shaped algae can grow up to 4 inches tall. Scientists love studying it because its nucleus is located in the stem, proving that even a single cell can have complex structures.

6. Spirostomum

File:Spirostomum macronucleus.jpg
Openverse

This enormous single-celled protozoan can stretch up to 4 millimeters long. It moves with incredible speed, contracting its body in milliseconds to escape predators.

7. Stentor

Dwa stentory
Openverse

Stock photo suggestion: A funnel-shaped microorganism under a microscope.

Often called the “trumpet animalcule,” Stentor is a single-celled organism that can grow up to 2 millimeters long. It has tiny hair-like structures that help it sweep in food.

8. Chaos carolinense

File:Protozoa collage 2.jpg
Openverse

This giant amoeba, also known as the “chaos amoeba,” can reach nearly 5 millimeters in length. It has hundreds of nuclei and constantly changes shape as it moves.

9. Thiomargarita namibiensis

Thiomargarita namibiensis
Openverse

Nicknamed the “sulfur pearl of Namibia,” this bacterium can grow as large as 0.75 millimeters—huge for bacteria! It stores sulfur inside its body, making it appear bright and shiny.

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10. Syringammina fragilissima

Syringammina fragilissima
Youtube | SciShow

This deep-sea giant can grow up to 4 inches wide, making it one of the largest single-celled organisms ever discovered. It builds a protective casing around itself, creating a structure that looks like coral.

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