Top 15 Best Fifth-Round NFL Draft Picks of All Time

The NFL Draft is full of surprises, with superstars often emerging from unexpected places. The fifth round, in particular, has given rise to some of the league’s most iconic players.

Here’s a look at the 15 best fifth-round draft picks in NFL history:

15. Mike Webster (1974, Pittsburgh Steelers)

Mike Webster
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The heart and soul of the Steelers’ offensive line during their dynasty years, Mike Webster is widely regarded as one of the greatest centers in NFL history. A four-time Super Bowl champion and nine-time Pro Bowler, Webster’s toughness and leadership set the standard for future generations.

14. Zach Thomas (1996, Miami Dolphins)

Zach Thomas
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Undersized but relentless, Zach Thomas became a cornerstone of the Dolphins’ defense. Thomas, a seven-time Pro Bowler and five-time First-Team All-Pro, has instincts and a strong work ethic that have earned him a spot in the Pro Football Hall of Fame.

13. Richard Sherman (2011, Seattle Seahawks)

Richard Sherman
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An integral part of the Seahawks’ “Legion of Boom” defense, Richard Sherman’s intelligence and tenacity made him one of the best cornerbacks of his era. He’s a five-time Pro Bowler, Super Bowl champion, and a master of clutch moments.

12. Kevin Greene (1985, Los Angeles Rams)

Kevin Greene
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Kevin Greene ranks third all-time in career sacks with 160. A relentless pass rusher, Greene was a five-time Pro Bowler, two-time First-Team All-Pro, and a Hall of Fame inductee.

11. Stefon Diggs (2015, Minnesota Vikings)

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Known for his precise route running and playmaking ability, Stefon Diggs became an elite wide receiver. His memorable “Minneapolis Miracle” catch and subsequent success with the Buffalo Bills have cemented his status as a top-tier NFL star.

10. Herschel Walker (1985, Dallas Cowboys)

Herschel Walker
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Herschel Walker was a dual-sport athlete whose NFL career featured impressive rushing and receiving stats. Though famously traded in a blockbuster deal, Walker’s impact on the field and his role in reshaping teams’ futures make him an unforgettable fifth-round pick.

9. George Kittle (2017, San Francisco 49ers)

George Kittle
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One of the premier tight ends in the league today, George Kittle’s combination of blocking and receiving skills is unmatched. A multi-time Pro Bowler, Kittle’s energy and leadership have made him the centerpiece of the 49ers’ offense.

8. Shane Lechler (2000, Oakland Raiders)

Shane Lechler
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Often considered the greatest punter of all time, Shane Lechler’s career was defined by his powerful leg and remarkable consistency. A six-time First-Team All-Pro, Lechler changed the way punters are valued in the NFL.

7. Rodney Harrison (1994, San Diego Chargers)

Rodney Harrison
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A hard-hitting safety, Rodney Harrison was the backbone of several dominant defenses. A two-time Super Bowl champion with the Patriots, Harrison’s physicality and leadership earned him a spot in the Patriots Hall of Fame.

6. Mark Anderson (2006, Chicago Bears)

Mark Anderson
Wikipedia

Mark Anderson burst onto the scene with 12 sacks as a rookie, helping the Bears reach the Super Bowl. Though his career had its ups and downs, Anderson’s early impact makes him a noteworthy fifth-round find.

5. La’Roi Glover (1996, Oakland Raiders)

La'Roi Glover
Wikipedia

La’Roi Glover was a dominant force on the defensive line, earning six Pro Bowl selections and an NFL Defensive Player of the Year award. His ability to disrupt offenses as a defensive tackle was extraordinary.

Read More: The Top 15 NFL Draft Classes of All Time

4. Lester Hayes (1977, Oakland Raiders)

Lester Hayes
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A key figure in the Raiders’ defensive success, Lester Hayes was known for his sticky coverage and innovative use of Stickum. A two-time Super Bowl champion and five-time Pro Bowler, Hayes was one of the league’s premier cornerbacks.

Read More: The 29 Most Successful NFL Seasons Ever

3. Tyreek Hill (2016, Kansas City Chiefs)

Tyreek Hill, Khaleke Hudson (51615697528)
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Nicknamed “Cheetah” for his blazing speed, Tyreek Hill is one of the most explosive playmakers in NFL history. A seven-time Pro Bowler and two-time Super Bowl champion (as of 2025), Hill’s versatility as a receiver and returner has redefined offensive strategy.

Read More: Top 14 Best Seventh-Round NFL Draft Picks of All Time

2. Jerry Azumah (1999, Chicago Bears)

Jerry Azumah
Openverse

Initially a running back in college, Jerry Azumah transitioned to cornerback in the NFL and excelled as a return specialist. A Pro Bowler and one of the best kickoff returners of his era, Azumah’s versatility made him a valuable asset.

Read More: The 30 Best Draft Picks in the History of the NFL

1. Robert Mathis (2003, Indianapolis Colts)

Robert Mathis
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Robert Mathis terrorized quarterbacks throughout his career, finishing with 123 sacks. A five-time Pro Bowler and Super Bowl champion, Mathis’s strip-sack ability was legendary, and he remains the NFL’s all-time leader in forced fumbles.

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