In the NFL, pairing big names together is supposed to be a recipe for success. But sometimes, star power can’t overcome a total lack of chemistry, on or off the field.
From quarterbacks and wide receivers who never got on the same page to coaching tandems that fizzled fast, these duos looked great in headlines but left fans scratching their heads on Sundays. Hype doesn’t win games—cohesion does.
16. Jay Cutler and Brandon Marshall (Chicago Bears)

Reunited in Chicago after their Denver days, this duo promised fireworks. Instead, fans got miscommunication and sideline drama.
15. Odell Beckham Jr. and Baker Mayfield (Cleveland Browns)

They were supposed to light up the scoreboard. Instead, they just lit up Twitter with rumors and frustration.
14. Carson Wentz and Frank Reich (Indianapolis Colts)

Reich was supposed to fix Wentz. It turns out that not even his former coach could salvage that situation.
13. Randy Moss and Kerry Collins (Oakland Raiders)

Moss in silver and black sounded like a dream. Too bad the quarterback situation was more of a nightmare.
12. Chip Kelly and LeSean McCoy (Philadelphia Eagles)

Speed, tempo, and talent were all there on paper. However, their relationship soured quickly, and the consequences followed.
11. Josh Allen and Kelvin Benjamin (Buffalo Bills)

Buffalo hoped Benjamin would be Allen’s big target. Instead, he looked checked out from the jump.
10. Mark Sanchez and Santonio Holmes (New York Jets)

The Jets tried to pair a young QB with a Super Bowl-winning wideout. It didn’t take long for the finger-pointing to start.
9. Jimmy Garoppolo and Josh McDaniels (Las Vegas Raiders)

They had history in New England, but Vegas wasn’t the place for a reunion tour. Injuries, turnovers, and a whole lot of losing followed.
8. Matt Patricia and Matthew Stafford (Detroit Lions)

Patricia came in like a rocket scientist with answers. Stafford just looked more and more miserable with each passing game.
7. Donovan McNabb and Mike Shanahan (Washington)

A future Hall of Fame coach and a six-time Pro Bowler seemed like a solid match. The reality was a midseason benching and a whole lot of awkward.
6. Trevor Lawrence and Urban Meyer (Jacksonville Jaguars)

This was supposed to be the start of something special. Instead, it was a masterclass in dysfunction.
5. Derek Carr and Davante Adams (Las Vegas Raiders)

They were college teammates and best friends. But in the NFL, the magic didn’t carry over.
4. Brett Favre and Brad Childress (Minnesota Vikings)

Their first season brought promise. Year two brought miscommunication, injuries, and a dramatic collapse.
3. Tony Romo and Roy Williams (Dallas Cowboys)

Dallas paid big to bring Roy in from Detroit. He just never quite fit into Romo’s rhythm.
2. Russell Wilson and Nathaniel Hackett (Denver Broncos)

This was supposed to be a fresh start for both guys. Instead, it was one of the messiest seasons in recent memory.
1. Tom Brady and Antonio Brown (Tampa Bay Buccaneers)

They won a Super Bowl together, sure. But the off-field chaos and abrupt endings made this duo more infamous than iconic.
Read More: Ranking the 14 Greatest NFL Duos of All Time